Description
Nutramedix
Stevia is an extract from Stevia rebaudiana, having up to 300 times the sweetness of sugar. Stevia has garnered attention with the rise in demand for low-carbohydrate, low-sugar food alternatives. Nutramedix Stevia was identified as “Stevia A” in a study published in 2015 where it was shown to be more effective than doxycycline in eliminating Borreliaburgdorferi, in all morphologic forms. It also demonstrated a significant effect in eliminating B.burgdorferi biofilms which were exacerbated when using doxycycline.
Some Reported Medicinal Properties
ANTI-ACNE
ANTI-BACTERIAL
ANTI-CANDIDIASIS
ANTI-DANDRUFF
ANTI-DERMATITIS
ANTI-DIABETES
ANTI-CYSTITIS
ANTI-DYSPEPTIC
ANTI-GINGIVITIS
ANTI-HEARTBURN
ANTI-INFLAMMATORY BOWEL DISEASE
ANTI-NEPHROPATHY
ANTI-OBESITY
ANTI-OSTEOPOROTIC
ANTIOXIDANT
ANTI-RASH
ANTISEPTIC
ANTI-TOOTH DECAY
ANTI-TUMOR
DIURETIC
HYPOGLYCEMIC
HYPOTENSIVE
NATRIURETIC
PRO-ENERGY
Research On NutraMedix Product
IN VITRO – LYME DISEASE
Priyanka A.S. Theophilus M.S., Eva Sapi Ph.D. (2013). In Vitro Effect of Peruvian Antimicrobial Agents on Borrelia burgdorferi Full Article
IN VIVO – ACUTE ORAL TOXICITY TESTS
An acute oral toxicity study was conducted by the University of Guayaquil, Ecuador concluding that Stevia did not produce toxic effects, thus the product is considered practically innocuous for humans when administered in the acute form. Therefore; studies of acute toxicity at higher doses in humans are not necessary. Full Article
LYME
Theophilus, P. A. S., Victoria, M. J., Socarras, K. M., Filush, K. R., Gupta, K., Luecke, D. F., & Sapi, E. (2015). Effectiveness of Stevia rebaudiana whole leaf extract against the various morphological forms of Borrelia burgdorferi in vitro. European Journal of Microbiology and Immunology, 5(4), 268-280. Full Article
Medical Conditions [peer-reviewed journals]
HUMAN ROTAVIRUS (HRV)
Takahashi, K., Matsuda, M., Ohashi, K., Taniguchi, K., Nakagomi, O., Abe, Y., … & Shigeta, S. (2001). Analysis of anti-rotavirus activity of extract from Stevia rebaudiana. Antiviral research, 49(1), 15-24. Full Article
DIABETES
Zaidan, U. H., Zen, N. I. M., Amran, N. A., Shamsi, S., & Gani, S. S. A. (2019). Biochemical evaluation of phenolic compounds and steviol glycoside from Stevia rebaudiana extracts associated with in vitro antidiabetic potential. Biocatalysis and agricultural biotechnology, 18, 101049. Full Article
Ahmad, U., & Ahmad,R. S. (2018). Antidiabetic property of aqueous extract of Stevia rebaudiana Bertoni leaves in Streptozotocin-induced diabetes in albino rats. BMC complementary and alternative medicine, 18(1),179. Full Article
Carrera-Lanestosa, A.,Moguel-Ordóñez, Y., & Segura-Campos, M. (2017). Stevia rebaudiana Bertoni: a natural alternative for treating diseases associated with metabolic syndrome. Journal of medicinal food, 20(10), 933-943. Full Article
AbdElwahab, A. H.,Yousuf, A. F., Ramadan, B. K., & Elimam, H. (2017). Comparative Effects of Stevia rebaudiana and Aspartame on hepato-renal function of diabetic rats: Biochemical and Histological Approaches. Journal of Applied Pharmaceutical Science Vol, 7(08), 034-042. Full Article
Patil, A., Nirmal, S.,Pattan, S., Tambe, V., & Tare, M. (2012). Antidiabetic effect of polyherbal combinations in STZ induced diabetes involve inhibition of α-amylase and α-glucosidase with amelioration of lipid profile. Phytopharmacology, 2(1), 46-57. Full Article
Pallarés, Á., Carrasco,G., Nava, Y., Pallarés, O., Pérez, I., Rifá, R., & Rodríguez, M. (2015). Effectiveness and safety of Stevia rebaudiana dried leaves as an adjuvant in the short-term treatment of type 2 diabetes: A randomized, controlled, cross-over and double-blinded trial. JMed Plant Herbal Ther Res, 3, 16-26. Full Article
Ruiz-Ruiz, J. C.,Moguel-Ordoñez, Y. B., Matus-Basto, A. J., & Segura-Campos, M. R. (2015). Antidiabetic and antioxidant activity of Stevia rebaudiana extracts (Var. Morita) and their incorporation into a potential functional bread. Journal of food science and technology, 52(12),7894-7903. Full Article
Parimalavalli, R.,& Radhaisri, S. (2011). Glycaemic index of stevia product and its efficacy on blood glucose level in type 2 diabetes. Indian Journal of Science and Technology, 4(3), 318-321. Full Article
Sharma, R., Yadav, R.,& Manivannan, E. (2012). Study of effect of Stevia rebaudiana bertoni on oxidative stress in type-2 diabetic rat models. Biomedicine & Aging Pathology, 2(3), 126-131. Full Article
Maki, K. C., Curry, L.L., Reeves, M. S., Toth, P. D., McKenney, J. M., Farmer, M. V., … & Carakostas, M. C. (2008). Chronic consumption of rebaudioside A, a steviol glycoside, in men and women with type 2 diabetes mellitus.Food and Chemical Toxicology, 46(7), S47-S53. Full Article
Sumon, M. H., Mostofa,M., Jahan, M. S., Kayesh, M. E. H., & Haque, M. A. (2008). Comparative efficacy of powdered form of stevia (Stevia rebaudiana Bertoni) leaves and glimepiride in induced diabetic rats. Bangl. J. Vet. Med, 6(2), 211-215. Full Article
Dyrskog, S. E. U.,Jeppesen, P. B., Colombo, M., Abudula, R., & Hermansen, K. (2005). Preventive effects of a soy-based diet supplemented with stevioside on the development of the metabolic syndrome and type 2 diabetes in Zucker diabetic fatty rats. Metabolism, 54(9),1181-1188. Full Article
Giri, A., Rao, H. R.,& Ramesh, V. (2014). Effect of partial replacement of sugar with stevia on the quality of kulfi.Journal of food science and technology, 51(8), 1612-1616. Full Article
Ozbayer, C., Kurt, H.,Kalender, S., Ozden, H., Gunes, H. V., Basaran, A., … & Degirmenci, I.(2011). Effects of Stevia rebaudiana (Bertoni) extract and N-nitro-L-arginine on renal function and ultrastructure of kidney cells in experimental type 2 Diabetes. Journal of medicinal food, 14(10), 1215-1222. Full Article
Anton, S. D., Martin,C. K., Han, H., Coulon, S., Cefalu, W. T., Geiselman, P., & Williamson, D.A. (2010). Effects of stevia, aspartame, and sucrose on food intake, satiety, and postprandial glucose and insulin levels. Appetite, 55(1), 37-43. Full Article
Assaei, R., Mokarram,P., Dastghaib, S., Darbandi, S., Darbandi, M., Zal, F., … & Omrani, G. H.R. (2016). Hypoglycemic effect of aquatic extract of stevia in pancreas of diabetic rats: PPARγ-dependent regulation or antioxidant potential. Avicenna journal of medical biotechnology, 8(2), 65. Full Article
Gupta, E., Purwar, S.,Sundaram, S., & Rai, G. K. (2013). Nutritional and therapeutic values of Stevia rebaudiana: A review. Journal of Medicinal Plants Research, 7(46), 3343-3353. Full Article
Shivanna, N., Naika,M., Khanum, F., & Kaul, V. K. (2013). Antioxidant, anti-diabetic and renal protective properties of Stevia rebaudiana. Journal of Diabetes and its Complications, 27(2), 103-113. Full Article
Kujur, R. S., Singh,V., Ram, M., Yadava, H. N., Singh, K. K., Kumari, S., & Roy, B. K. (2010). Antidiabetic activity and phytochemical screening of crude extract of Stevia rebaudiana in alloxan-induced diabetic rats. Pharmacognosy research, 2(4), 258. Full Article
Ritu, M., & Nandini, J. (2016). Nutritional composition of Stevia rebaudiana, a sweet herb, and its hypoglycaemic and hypolipidaemic effect on patients with non‐insulin dependent diabetes mellitus. Journal of the Science of Food and Agriculture, 96(12), 4231-4234. Full Article
Laribi, B., Rouatbi,N., Kouki, K., & Bettaieb, T. (2012). In vitro propagation of Stevia rebaudiana (Bert.)-A non-caloric sweetener and antidiabetic medicinal plant. Int. J. Med. Arom. Plants, 2(2), 333-339. Full Article
Mohd-Radzman, N. H.,Ismail, W. I. W., Adam, Z., Jaapar, S. S., & Adam, A. (2013). Potential roles of Stevia rebaudiana Bertoni in abrogating insulin resistance and diabetes: a review. Evidence-Based Complementary and Alternative Medicine, 2013. Full Article
Jeppesen, P. B.,Gregersen, S., Poulsen, C. R., & Hermansen, K. (2000). Stevioside acts directly on pancreatic β cells to secrete insulin: Actions independent of cyclic adenosine monophosphate and adenosine triphosphate—sensitive K+-channel activity. Metabolism, 49(2), 208-214. Full Article
HYPERTENSION
Gandhi, S., Gat, Y., Arya, S.,Kumar, V., Panghal, A., & Kumar, A. (2018). Natural sweeteners: health benefits of stevia. Foods andRaw Materials, 6(2), Gandhi-S. Full Article
Rizwan, F., Rashid, H. U.,Yesmine, S., Monjur, F., & ChatteFrjee, T. K. (2018). Preliminary analysis of the effect of Stevia (Stevia rebaudiana) in patients with chronic kidney disease (stage I to stageIII). Contemporary clinical trials communications, 12,17-25. Full Article
Khiraoui, A., & Guedira, T.(2018). Effect of Stevia rebaudiana, sucrose and aspartame on human health: A comprehensive. Journal of Medicinal Plants,6(1), 102-108. Full Article
Amin, K., Ozgen, S., & Selamoglu, Z. (2017). Stevia rebaudiana: A potential boon for human health. SMJ Med Plants Stud, 1, 1005. Full Article
Ruiz-Ruiz, J. C., Moguel-Ordoñez,Y. B., & Segura-Campos, M. R. (2017). Biological activity of Stevia rebaudiana Bertoni and their relationship to health. Critical reviews in food science and nutrition, 57(12), 2680-2690. Full Article
Marcinek, K., & Krejpcio, Z.(2016). Stevia rebaudiana Bertoni: health promoting properties and therapeutic applications. Journalfür Verbraucherschutz und Lebensmittelsicherheit, 11(1), 3-8. Full Article
Ranjan, R., Jaiswal, J., & Jena,J. (2011). Stevia as a natural sweetener. IntJ Res Pharm Chem, 1, 21-9. Full Article
Arora, E., Khajuria, V., Kumar,S., Gillani, Z., Sadiq, S., & Tandon, V. R. (2010). Stevia: A promising herbal sweeteners. JKscience, 12(4), 212. Full Article
Tirapelli, C. R., Ambrosio, S.R., de Oliveira, A. M., & Tostes, R. C. (2010). Hypotensive action of naturally occurring diterpenes: atherapeutic promise for the treatment of hypertension. Fitoterapia,81(7), 690-702. Full Article
Ferri, L. A., Alves‐Do‐Prado, W.,Yamada, S. S., Gazola, S., Batista, M. R., & Bazotte, R. B. (2006). Investigation of the antihypertensive effect of oral crude stevioside in patients with mild essential hypertension. Phytotherapy Research:An International Journal Devoted to Pharmacological and ToxicologicalEvaluation of Natural Product Derivatives, 20(9), 732-736. Full Article
Singh, S. D., & Rao, G. P.(2005). Stevia: The herbal sugar of 21st century. Sugar tech, 7(1),17-24. Full Article
Chan, P., Tomlinson, B., Chen, Y.J., Liu, J. C., Hsieh, M. H., & Cheng, J. T. (2000). A double‐blind placebo‐controlled study of the effectiveness and tolerability of oral stevioside in human hypertension. British journal of clinical pharmacology, 50(3), 215-220. Full Article
Medicinal Properties [peer-reviewed journals]
ANTIBACTERIAL
Fazal, H. I. N. A., Ahmad, N., Ullah, I., Inayat, H., Khan, L., & Abbasi, B. H. (2011). Antibacterial potential in Parthenium hysterophorus, Stevia rebaudiana and Ginkgo biloba. Pak. J. Bot, 43(2), 1307-1313. Full Article
ANTIDIABETIC
Kujur, R. S., Singh, V., Ram, M., Yadava, H. N., Singh, K. K., Kumari, S., & Roy, B. K. (2010). Antidiabetic activity and phytochemical screening of crude extract of Stevia rebaudiana in alloxan-induced diabetic rats. Pharmacognosy research, 2(4), 258. Full Article
Ahmad, U., & Ahmad, R. S. (2018). Antidiabetic property of aqueous extract of Stevia rebaudiana Bertoni leaves in Streptozotocin-induced diabetes in albino rats. BMC complementary and alternative medicine, 18(1),179. Full Article
Assaei, R., Mokarram, P., Dastghaib, S., Darbandi, S.,Darbandi, M., Zal, F., … & Omrani, G. H. R. (2016). Hypoglycemic effect of aquatic extract of Stevia in pancreas of diabetic rats: PPARγ-dependent regulation or antioxidant potential. Avicenna journal of medical biotechnology,8(2), 65. Full Article
Bender, C., Graziano, S., & Zimmermann, B. F.(2015). Study of Stevia rebaudiana Bertoni antioxidant activities and cellular properties. Internationaljournal of food sciences and nutrition, 66(5),553-558. Full Article
Sumon, M. H., Mostofa, M., Jahan, M. S., Kayesh, M. E.H., & Haque, M. A. (2008). Comparative efficacy of powdered form of stevia (Stevia rebaudiana Bertoni) leaves and glimepiride in induced diabetic rats. BangladeshJournal of Veterinary Medicine, 6(2), 211-215. Full Article
Ferreira, E. B., Neves, F. D. A. R., da Costa, M. A. D.,do Prado, W. A., Ferri, L. D. A. F., & Bazotte, R. B. (2006). Comparative effects of Stevia rebaudiana leaves and stevioside on glycaemia and hepatic gluconeogenesis. Planta medica, 72(08), 691-696. Full Article
ANTIMICROBIAL
Ghosh, S., Subudhi, E., & Nayak, S. (2008). Antimicrobial assay of Stevia rebaudiana Bertoni leaf extracts against 10 pathogens. Int J Integr Biol, 2(1), 1-5. Full Article
Jayaraman, S., Manoharan, M. S., & Illanchezian, S. (2008). In-vitro antimicrobial and antitumor activities of Stevia rebaudiana (Asteraceae) leaf extracts. Tropical Journal of Pharmaceutical Research, 7(4), 1143-1149. Full Article
Debnath, M. (2007). Clonal propagation and antimicrobial activity of an endemic medicinal plant Stevia rebaudiana. Journal of medicinal plants research, 2(2), 045-051. Full Article
Tadhani, M. B., & Subhash, R. (2006). In vitro antimicrobial activity of Stevia rebaudiana Bertoni leaves. Tropical Journal of Pharmaceutical Research, 5(1), 557-560. Full Article
ANTIOXIDANT
Barba, F. J., Criado, M. N., Belda-Galbis, C. M., Esteve, M. J., & Rodrigo, D. (2014). Stevia rebaudiana Bertoni as a natural antioxidant/antimicrobial for high pressure processed fruit extract: Processing parameter optimization. Food Chemistry, 148, 261-267. Full Article
Shukla, S., Mehta, A., Mehta, P., & Bajpai, V. K. (2012). Antioxidant ability and total phenolic content of aqueous leaf extract of Stevia rebaudiana Bert. Experimental and Toxicologic Pathology, 64(7-8), 807-811. Full Article
Kim, I. S., Yang, M., Lee, O. H., & Kang, S. N. (2011). The antioxidant activity and the bioactive compound content of Stevia rebaudiana water extracts. LWT-Food Science and Technology, 44(5), 1328-1332. Full Article
Shukla, S., Mehta, A., Bajpai, V. K., & Shukla, S. (2009). In vitro antioxidant activity and total phenolic content of ethanolic leaf extract of Stevia rebaudiana Bert. Food and Chemical Toxicology, 47(9), 2338-2343 Full Article
Tadhani, M. B., Patel, V. H., & Subhash, R. (2007). In vitro antioxidant activities of Stevia rebaudiana leaves and callus. Journal of food composition and Analysis, 20(3-4), 323-329. Full Article
CHOLESTEROL-LOWERING
Ahmad, U., Ahmad, R. S., Arshad,M. S., Mushtaq, Z., Hussain, S. M., & Hameed, A. (2018). Antihyperlipidemic efficacy of aqueous extract of Stevia rebaudiana Bertoni in albino rats. Lipids in health anddisease, 17(1), 175. Full Article
Aghajanyan, A., Movsisyan, Z.,& Trchounian, A. (2017). Antihyperglycemic and antihyperlipidemic activity of hydroponic stevia rebaudiana aqueous extract in hyperglycemia induced by immobilization stress in rabbits. BioMed research international, 2017. Full Article
Ritu, M., & Nandini, J.(2016). Nutritional composition ofStevia rebaudiana, a sweet herb, and its hypoglycaemic and hypolipidaemiceffect on patients with non‐insulin dependent diabetes mellitus. Journalof the Science of Food and Agriculture, 96(12), 4231-4234. Full Article
Adisakwattana, S., Intrawangso,J., Hemrid, A., Chanathong, B., & Mäkynen, K. (2012). Extracts of edible plants inhibit pancreatic lipase, cholesterol esterase and cholesterol micellization, and bind bile acids. Food Technology and Biotechnology, 50(1), 11. Full Article
Goyal, S. K., Samsher, G. R.,& Goyal, R. K. (2010). Stevia (Stevia rebaudiana) a bio-sweetener: a review. IntJ Food Sci Nutr, 61(1), 1-10. Full Article
Mohan, K., & Robert, J.(2009). Protective Effect of Stevia rebaudiana Bertoni on Cadmium-induced Nephrotoxicity in Male Albino Rats InternationalJournal of Biomedical and Pharmaceutical Sciences., 3(1),26-28. Full Article
Savita, S. M., Sheela, K., Sunanda, S., Shankar, A. G.,Ramakrishna, P., & Sakey, S. (2004). Health implications of Stevia rebaudiana. Journal of Human Ecology, 15(3), 191-194. Full Article
Conference Presentations
Cowden Support Program for Lyme: Observational Study – Dublin, Ireland – June, 2012 Armin Schwarzbach, MD PhD Full Video
Patient Reports
“Has a great sweet taste, I use this for my Lyme disease, and I did herx on it at first, so I had to back off a little, but it works fine, and since its best for me to stay away from sugar, it’s a great sweetener, i put in my water with a squeeze of lemon. love it.” – A.S
“I have to take a few antimicrobials for a bacterial infection, and this stevia definitely improves the taste!” – K.L
“Curbs sugar craving. Excellent for anyone with Lyme disease or a that’s looking for a good quality extract.” – M.L
“I’ve been addicted to sugar since I was 5. My doctor told me that I was going into pre-diabetes and that I better make a change. He told me about NutraMedix Stevia – that it wasn’t a fractured, processed version of the Stevia plant. He said that it came from the plant as a whole food and that’s been my goal ever since – to get healthy by eating whole foods and no sugar. I’m proud to say I’ve lost 50 pounds and I no longer crave sugar. This Stevia is really good.” -R.M.
Dosage Information
Add 3 or more drops as desired to food or beverages. As an antimicrobial, use 30 drops twice daily. Nutramedix Stevia contains no added sugars.
Safety Information
An acute oral toxicity study was conducted by the University of Guayaquil, Ecuador concluding that Stevia did not produce toxic effects, thus the product is considered practically innocuous for humans when administered in the acute form. Therefore; studies of acute toxicity at higher doses in humans are not necessary. Full Article